Actively and Passively Induced Arthus Reactions in the Mouse.

Publisher Website
Google Scholar
Abstract
Arthus reactions were produced in mice 35 days following sensitization by 3 intraperitoneal injections of bovine plasma albumin in adjuvant. More antibody was required to passively sensitize mice than the amount required to sensitize guinea pigs. Reverse Arthus reactions were produced with 0.06 and 0.005 mg mouse anti-bovine plasma albumin (BPA) N in mice and guinea pigs, respectively. Passive Arthus reactions were not detected in mice injected with 0.02 mg rabbit anti-ovalbumin, whereas minimal reactions were produced in guinea pigs with 0.005 mg anti-ovalbumin.