The Reaction of b-Aminoenones with a-Amino Derivatives. Synthesis of 2-Functionalized Pyrroles

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Abstract
.beta.-Aminoenones react with ethyl glycinate, .alpha.-aminoacetonitrile and .alpha.-aminoacetamide hydrochlorides leading to 2-funtionalized pyrroles. Although the transamination is a high-yield process, the transformation of the intermediate, in both basic or thermally induced conditions, affords the corresponding pyrroles in poor to moderate yields.
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