Disseminated Experimental South American Blastomycosis of the Guinea Pig;
- 1 January 1963
- journal article
- research article
- Published by S. Karger AG in Pathobiology
- Vol. 26 (1) , 29-43
- https://doi.org/10.1159/000161352
Abstract
Inoculation in guinea pigs of a standardized suspension of culture of Paracoccidioides brasiliensis by heart puncture produces disseminated South American blastomycosis; lung, testes, eyes and skin being the sites more deeply affected by the parasite. A certain degree of adaptation of the fungus to the experimental animal and an increased virulence was noticed when a culture obtained after five serial passages to the guinea pig testes, with re-isolation of the fungus, was used. An immunological study of the experimental animal was also done, in an attempt to correlate it with the pathological findings.Keywords
This publication has 1 reference indexed in Scilit:
- A COMPARATIVE HISTOLOGIC AND IMMUNOLOGIC STUDY IN RABBITS OF INDUCED HYPERSENSITIVITY OF THE SERUM SICKNESS TYPEThe Journal of Experimental Medicine, 1953