Photoreactivity (365 nm) of Some Coumarins and 4′,5′-dihydro-furocoumarins with Nucleic acids
Open Access
- 1 November 1971
- journal article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 26 (11) , 1129-1136
- https://doi.org/10.1515/znb-1971-1111
Abstract
The Authors have studied the capacity to photoreact with native DNA and r-RNA using six coumarins and four 4′,5′-dihydro-furo-coumarins. Six of these substances have shown a definite photoreactivity both with DNA and r-RNA, even if in a very much lower extent in respect to that of skin-photosensitizing furocoumarins. The low capacity to photoreact with nucleic acids of these substances is discussed, also in connection with the absence of skin-photosensitizing activity.Keywords
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