Abstract
In Dictyostelium minutum the formation of aggregation centers is induced by single amoebae (founder cells), which can be distinguished from the other amoebae only a short time before the centers are founded. A method is described for selection of mutants blocked only in respect to center formation. A mutant (aggr-121) isolated by this technique can be combined with a center forming mutant to overcome the developmental block. Probably the differentiation of functional founder cells in aggr-121 is greatly reduced.

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