Diagnostic utility of sialosyl-Tn in discriminating carcinomatous cells from benign mesothelium in body cavity effusions.
- 1 January 1999
- journal article
- clinical trial
- Published by S. Karger AG in Acta Cytologica
- Vol. 43 (6) , 1079-1084
- https://doi.org/10.1159/000331356
Abstract
Detecting malignant cells in the setting of reactive mesothelium can be difficult. Several techniques have been tried but without widespread acceptance. Sialosyl-Tn (STn) is an aberrantly glycosylated precursor of the MN blood group antigen frequently expressed in carcinomas and dysplastic epithelium. We investigated the STn monoclonal antibody for its clinical utility as an isolated stain to discriminate benign mesothelium from malignant cells.Keywords
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