Detection of Splenosis and Ectopic Spleens with 99mTc‐Labelled Heat Damaged Autologous Erythrocytes in 90 Splenectomized Patients

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Abstract
Splenosis or ectopic spleens were detected in 22 of 45 patients splenectomized after either abdominal trauma or accidental lesions of the spleen during operation. The incidence of ectopic spleen tissue in various groups of splenectomized patients was investigated by a sensitive scanning method employing reinjection of 99mTc-labeled heat damaged autologous erythrocytes. Seven cases were found among 45 patients who underwent splenectomy for hematological reasons. The time span between the operation and a positive scan varied between 3 mo. and 11 yr. None of the patients in the hematological group with reoccurrence of spleen tissue presented any signs of relapse of their primary disorder. The only patient with overwhelming infection was a girl in whom splenectomy was performed for hereditary spherocytosis. She recovered from the sepsis and her scan was negative. Recurrence of spleen tissue is frequent after traumatic lesions of the spleen but rate after selective splenectomy for hematological reasons. This may account for the lesser tendency to overwhelming sepsis after post-traumatic splenectomy.

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