Clinical Evaluation of Different Fluid-filled Systems for Oesophageal Manometry

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Abstract
In a clinical study of esophageal manometry with fluid-filled catheters, both a non-perfused system and a perfused system with a syringe pump were compared to a system with a low-compliance perfusion pump, which served as a reference. Significantly lower values of motility amplitudes, motility derivatives, and partly of LES [lower esophageal sphincter] pressures, and a time delay of up to 0.5 s of the amplitude maximum were obtained with the non-perfused system and the system with a syringe pump in comparison to the low-compliance system. Since the esophageal function can be erroneously evaluated by use of a non-perfused system or a perfused system with a syringe pump, such systems cannot be recommended for clinical use.