Regulation of the Adrenal Cortex Secretory Pattern by Adrenocorticotropin
- 30 June 1967
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3783) , 1753-1755
- https://doi.org/10.1126/science.156.3783.1753
Abstract
Adrenal gland homogenates from rabbits stimulated for 28 days with adrenocorticotropin have been shown to synthesize cortisol. The total amount of cortisol formed was the same whether progesterone-4-14C or Δ5-pregnenolone-4-14C was used as exogenous substrate. However, when Δ5-pregnenolone substrate was used the specific activity of the isolated cortisol was four times as great as when progesterone was used.Keywords
This publication has 2 references indexed in Scilit:
- Adrenal Steroid Secretion in Rabbits Following Prolonged ACTH AdministrationExperimental Biology and Medicine, 1965
- Changes in Patterns of Secretion of Corticosteroids in Rabbits after Prolonged Treatment with ACTH.Experimental Biology and Medicine, 1954