Treatment of Malaria with Oral or Intravenous Plaquenil
- 1 September 1953
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 2 (5) , 805-807
- https://doi.org/10.4269/ajtmh.1953.2.805
Abstract
Summary Eighty-two Hondurans were treated for malaria with 7-chloro-4-[4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino] quinoline diphosphate (Plaquenil). Sixty-eight of them (21 with P. falciparum, 47 with P. vivax) were given a single oral dose of 1.25 gm. Fourteen others with P. falciparum infections were given an intravenous dose of 0.36 gm. in 500 cc. of normal saline solution. Both the immediate and the late results were encouraging. Toxic side-effects of the drug were not encountered. Plaquenil, therefore, warrants further investigation; its experimental use will be continued in this and other locations.Keywords
This publication has 2 references indexed in Scilit:
- TREATMENT OF MALARIA WITH A SINGLE DOSE OF AMODIAQUINE OR CHLOROQUINEJAMA, 1952
- THE TREATMENT OF PLASMODIUM-FALCIPARUM MALARIA WITH A SINGLE DOSE ANTIMALARIAL - PRELIMINARY REPORT OF THE USE OF HYDROXYCHLOROQUINE, 7-CHLORO-4(4'-(N-ETHYL-N-B-HYDROXYETHYLAMINO)-1-METHYLBUTYLAMINO)-QUINOLINE DIPHOSPHATE1952