Lactic Dehydrogenase Virus-Induced Immune Complex Type of Glomerulonephritis
Open Access
- 1 May 1971
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 106 (5) , 1260-1263
- https://doi.org/10.4049/jimmunol.106.5.1260
Abstract
Mice persistently infected with lactic dehydrogenase virus (LDV) show granular deposits of host IgG, C3 and viral antigen in their renal glomeruli. Specific anti-LDV antibody is concentrated in these deposits. The mild glomerulonephritis observed is apparently related to trapping of circulating virus-antibody complexes in the glomerular filter.Keywords
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