Effect of Leukocyte-Promoting Factor (LPF) on Survival of X-Irradiated Mice.
- 1 November 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (2) , 541-542
- https://doi.org/10.3181/00379727-81-19933
Abstract
Treatment of irradiated mice with leukocytosis-promoting factor did not increase their 30-day survival. This fact strongly suggests that if survival of irradiated mice into which normal spleens have been implanted is due to a "humoral" factor released by the spleen, such a factor is unrelated to the specific leukocyte-promoting factor obtained from sterile exudates. LPF, a logical therapeutic agent, is ineffective in reducing X-ray mortality in mice.Keywords
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