Plasmodium falciparum: Increased and Multiple Invasion During Short Periods of Time
- 1 January 1990
- journal article
- research article
- Published by Wiley in The Journal of Protozoology
- Vol. 37 (1) , 47-49
- https://doi.org/10.1111/j.1550-7408.1990.tb01113.x
Abstract
We describe how to obtain an increased merozoite invasion of Plamodium falciparum into human erythrocytes during short periods of time. Using this procedure infected erythrocytes show multiple invasions (2-4 merozoites per erythrocyte), amplifying, several times, the effects of parasite entry into host cells. The procedure yields synchronous cultures (2-h age range) with parasitemia as high as 15%. It is posible to reach parasitemia of 50% or higher allowing for a 6-h invasion period.Keywords
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