Measuring conformational dynamics of biomolecules by single molecule fluorescence spectroscopy.
Top Cited Papers
- 1 September 2000
- journal article
- review article
- Published by Springer Nature in Nature Structural & Molecular Biology
- Vol. 7 (9) , 724-729
- https://doi.org/10.1038/78941
Abstract
Dynamic structural changes of macromolecules undergoing biochemical reactions can be studied using novel single molecule spectroscopy tools. Recent advances in applying such distance and orientation molecular rulers to biological systems are reviewed, and future prospects and challenges are discussed.Keywords
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