Analysis of mass transfer for immobilized cells in an extractive lactic acid fermentation
- 15 March 1991
- journal article
- research article
- Published by Wiley in Biotechnology & Bioengineering
- Vol. 37 (6) , 544-550
- https://doi.org/10.1002/bit.260370608
Abstract
The use of immobilization in extractive lactic acid fermentation by Lactobacillus delbrueckii is preferred. In this article, the mathematical simulations to examine the influences of substrate and product transport were performed to assess the overall performance. The simulations showed that transport of the substrate in k-carrageenan beads was not a rate limiting factor. However, the model observed significant buildup of inhibitory product in large beads. The model was validated through comparisons with the experimental results. Finally, the model was used to predict the performance of the extractive fermentation under different operating strategies.Keywords
This publication has 15 references indexed in Scilit:
- Bioreactor System with Solvent Extraction for Organic Acid ProductionaAnnals of the New York Academy of Sciences, 1987
- Measurement of effective diffusivities of lactose and lactic acid in 3% agarose gel membraneBiotechnology & Bioengineering, 1987
- Examination of substrate and product inhibition kinetics on the production of ethanol by suspended and immobilized cell reactorsBiotechnology & Bioengineering, 1987
- Diffusion in κ-carrageenan gel beadsBiotechnology & Bioengineering, 1986
- Modelling the effects of mass transfer on kinetics of propene epoxidation of immobilized Mycobacterium cells: 2. Product inhibitionEnzyme and Microbial Technology, 1986
- Cell immobilization in κ‐carrageenan for ethanol productionBiotechnology & Bioengineering, 1985
- Optimization of the activity in porous media of proton‐generating immobilized enzymatic reactions by weak acid facilitationBiotechnology & Bioengineering, 1985
- Mass transfer effects in fermentations using immobilized whole cellsEnzyme and Microbial Technology, 1985
- Ethanol production by extractive fermentationBiotechnology & Bioengineering, 1982
- A kinetic study of the lactic acid fermentation. Batch process at controlled pHJournal of Biochemical and Microbiological Technology and Engineering, 1959