Nonsubstrate Recognition Site Residues Are Involved in Testosterone Hydroxylation by Cytochrome P450 CYP 2C11
- 1 January 1999
- journal article
- research article
- Published by Elsevier in Archives of Biochemistry and Biophysics
- Vol. 361 (2) , 309-314
- https://doi.org/10.1006/abbi.1998.1003
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Elucidation of Amino Acid Residues Critical for Unique Activities of Rabbit Cytochrome P450 2B5 Using Hybrid Enzymes and Reciprocal Site-Directed Mutagenesis with Rabbit Cytochrome P450 2B4Archives of Biochemistry and Biophysics, 1996
- P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclaturePharmacogenetics, 1996
- cDNA-Directed Expression of Two Allelic Variants of Cytochrome P450 2C11 Using COS1 and SF21 Insect CellsArchives of Biochemistry and Biophysics, 1996
- Deuterium Isotope Effects on A-Ring and D-Ring Metabolism of Testosterone by CYP2C11: Evidence for Dissociation of Activated Enzyme-Substrate ComplexesBiochemistry, 1994
- Hydrophobic Side Chain Requirements for Lauric Acid and Progesterone Hydroxylation at Amino Acid 113 in Cytochrome P450 2C2, a Potential Determinant of Substrate SpecificityArchives of Biochemistry and Biophysics, 1993
- Alteration of cytochrome P-450 2C11-dependent testosterone metabolism in Gunn rat liverBiochimica et Biophysica Acta (BBA) - General Subjects, 1992
- Steroid metabolism by constitutive cytochromes P450The Journal of Steroid Biochemistry and Molecular Biology, 1992
- Further Studies on Chimeric P450 2C2/2C14 Having Testosterone 16β-Hydroxylase Activity Which Is Absent in the Parental P450s1The Journal of Biochemistry, 1992
- Studies on the rate-determining factor in testosterone hydroxylation by rat liver microsomal cytochrome P-450: Evidence against cytochrome P-450 isozyme:Isozyme interactionsArchives of Biochemistry and Biophysics, 1987
- A simple method for displaying the hydropathic character of a proteinJournal of Molecular Biology, 1982