Effect of Resection of Antrum and Duodenal Bulb on Sham-feeding-induced Inhibition of Canine Gastric Secretion

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Abstract
In dogs with Heidenhain pouches and esophageal and gastric fistulae, sham feeding inhibited pentagastrin-stimulated Heidenhain pouch acid output. Resection of the antrum and the duodenal bulb reduced or abolished the inhibitory effect of sham feeding in most dogs when the acid of the main stomach was diverted through the gastric cannula. Sham feeding inhibited Heidenhain pouch acid secretion at least partly by inducing a vagal release of an inhibitory hormone. This hormone was apparently released from the antrum and the duodenal bulb.

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