Pathogenesis of Acne Vulgaris

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Abstract
A DISEASE does not have to be fatal, incurable or physically crippling to be devastating. Acne vulgaris causes emotionally devastating effects by disfiguring the face that the adolescent turns to the world he is just beginning to confront.The lesions of acne are located in and around the specialized pilosebaceous follicles of the face and upper trunk. In most hair follicles the size of the sebaceous gland is roughly proportional to the size of the hair. In the acne area, however, rather wide follicles are shared by a small or even rudimentary hair and a very large sebaceous gland.Clinically, . . .