The Significance of the Microcyst Response: A Review

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Abstract
Epithelial microcysts have been identified as a significant corneal response to contact lens wear. The characteristics of the microcyst response are outlined and factors which influence the level of microcysts including lens type, oxygen transmissibility (Dk/L), and wear schedule are discussed. Understanding of the morphology, pathology, etiology, and clinical significance of microcysts is currently incomplete and various hypotheses are discussed.

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