Selective Review of Effects of Discontinuation of Drug Treatment: Some Implications and Problems

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Abstract
The research literature on the effects of discontinuation of drug treatment is reviewed. The implications and problems generated by the increasing body of evidence that the therapeutic effects of ataractic drugs do not transfer to the nondrug state are considered. Effort is also made to elucidate some of the problems which negative effects of drug withdrawal create for drug therapy. Directions are suggested for further research that should lead to increased understanding and knowledge in this area.