Artificial Sweeteners and Fetal Malformations: A Rumored Relationship

Abstract
The increasing number of pharmacologic agents available with and without prescription must constantly be assessed as possible teratogens. The suffering and disability that resulted from delay in recognizing the effect of thalidomide on the developing fetus demands a system of reporting that would quickly detect an increase in the malformation rate. The surveillance system recently developed in Sweden shows that this is feasible, but no such system is yet available to physicians in America. We have recently examined two infants coming from the same township in Upper New York State and presenting roughly the same assciation of unusual anomalies.

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