A New Protocol for a One-pot Synthesis of α-Amino Phosphonates by Reaction of Imines Prepared In Situ with Trialkylphosphites

25 July 2002

journal article
letter
Published by Georg Thieme Verlag KG in Synlett

Vol. 2002 (8) , 1347-1349
https://doi.org/10.1055/s-2002-32957

Abstract

Imines prepared in situ by reaction of aldehydes and ketones with primary amines in ethereal solution of LiClO₄ react readily at ambient temperature with trialkylphosphite to give high yields of α-amino phosphonates.

Keywords

AMINO PHOSPHONATE
IMINE
TRIALKYLPHOSPHITE
LITHIUM PERCHLORATE

This publication has 0 references indexed in Scilit: