PARATHYROID CARCINOMA ASSOCIATED WITH ACUTE PARATHYROID INTOXICATION

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Abstract
A case of parathyroid carcinoma associated with long standing hyperparathyroidism and acute parathyroid intoxication is presented. The serum Ca level is one of the highest values reported in man. The theories of the mechanism of sudden death in parathyroid poisoning are discussed. In the present case the most probable mechanism was increased cardiac irritability due to the high ratio of Ca to K resulting in ventricular fibrillation. It is suggested that the treatment of choice for parathyroid intoxication is prompt surgical intervention. It is emphasized that radical resection of parathyroid carcinomas should be employed where possible.