EVIDENCE FOR A SET OF CLOSELY LINKED AUTOSOMAL GENES THAT INTERACT WITH SEX-CHROMOSOME HETEROCHROMATIN IN DROSOPHILA MELANOGASTER
Open Access
- 25 July 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 86 (3) , 567-582
- https://doi.org/10.1093/genetics/86.3.567
Abstract
It is proposed that there exists a special region in the euchromatin of the left arm of chromosome 2 (contained within sections 31-32 of the standard salivary gland chromosome map) that is defined by a set of genes, each one of which interacts with a specific sex-chromosome heterochromatic segment. The evidence for the existence of this region is, first, the exhibition, mapping, and analysis of five different maternal-effect, embryonic semi-lethals located in region 31-32. Secondly, in each case the consequence of the maternal effect is markedly influenced by the amount of X- or Y-chromosome heterochromatin carried by the progeny of mutant mothers. The nature of this interaction and possible reasons for the existence of the cluster of autosomal genes are discussedThis publication has 6 references indexed in Scilit:
- A SEX-SPECIFIC, TEMPERATURE-SENSITIVE MATERNAL EFFECT OF THE DAUGHTERLESS MUTATION OF DROSOPHILA MELANOGASTERGenetics, 1976
- REDUNDANT GENESAnnual Review of Genetics, 1975