Role of Agglomeration in Calcium Oxalate Monohydrate Urolith Development
- 1 January 1992
- journal article
- research article
- Published by S. Karger AG in Nephron
- Vol. 61 (2) , 145-150
- https://doi.org/10.1159/000186862
Abstract
Formation of agglomerates of calcium oxalate monohydrate (COM) crystals on semi-batch precipitation peformed at conditions relevant to urolithiasis (37°C, pH = 6, initial ratio [Ca]/[Ox] = 10), but without any specific admixture, was followed by both optical and electron microscopy. COM crystals formed on precipitation developed into large agglomerates consisting of intergrown crystals by a mechanism of primary agglomeration. Primary agglomeration of COM crystals represents an important mechanism of COM renal calculi growth.Keywords
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