A REPORT OF PROGRESS ON THE USE OF EPHEDRINE IN A CASE OF MYASTHENIA GRAVIS

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Abstract
Prior to an attack of influenzal pneumonia in December, 1918, I was considered a healthy, robust person with a capacity for work and exertion above the average. My previous history included the usual childhood diseases, nose and throat infections for which there had been two tonsillectomies, and two attacks of pneumonia. A relapse following the influenzal pneumonia was characterized by a marked prostration and weakness, and a tachycardia which in the absence of organic disease was attributed to a toxic depression of the vagus. A phlebitis also occurred at this time. After several months in bed, during which these symptoms gradually improved, I resumed work in a research laboratory. The pulse rate was still above normal (from 100 to 120) and there was an increased fatigability. During the next five years, while working full time, there seemed to be an improvement in strength although exertion was followed by excessive fatigue

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