Inhibition and Enhancement of the Noradrenaline Constrictor Response by Methylxanthines

Abstract
Theophylline and caffeine either inhibited or potentiated the noradrenaline constrictor response in an isolated perfused mesenteric artery preparation. The type of response observed was dependent on both the concentration of noradrenaline and the concentration of methylxanthine. Theobromine produced only inhibition of the noradrenaline response.

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