Growth inhibition activity and bacteriophage and bacteriocinlike particles associated with different species of Clostridium

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Abstract
Thirty-four strains corresponding to 16 Clostridium spp. were examined for growth inhibition activity and production of phage and bacteriocinlike particles. Twenty-five strains inhibited growth of one or more of the other strains. The widest range of activity corresponded to C. bifermentans 18137 which inhibited growth of 23 strains. Cell-free filtrates of positive cultures were inactive with the exception of the one from C. bifermentans 18137. A wide variety of particles with diverse morphology was observed in lysates of cultures treated with mitomycin C (1 .mu.g/ml).