THE SITE AND TIME OF ONSET OF GROWTH HORMONE PRODUCTION IN THE BOVINE ADENOHYPOPHYSIS, DETERMINED BY THE FLUORESCENT ANTIBODY METHOD
- 1 January 1962
- journal article
- research article
- Published by S. Karger AG in Cells Tissues Organs
- Vol. 51 (3) , 198-208
- https://doi.org/10.1159/000142315
Abstract
Ih bovine adenohypophyses (embryos, fetuses and adults of various ages) the production of GH was investigated by the fluorescent antibody method. As in humans, it was found that the cells responsible are the acidophils. Growth hormone production was earliest demonstrable in fetuses of 18 cm, that is at about the 3rd month of pregnancy, and increased rapidly thereafter. By the adult stage, the nonfluorescent acidophils had become predominant; these are probably "resting" cells and the change represents the end of somatic growth.Keywords
This publication has 2 references indexed in Scilit:
- THE DEVELOPMENT OF HUMAN HYPOPHYSIS AND DIFFERENTIATION OF CELLS OF ITS ANTERIOR LOBE DURING EMBRYONIC LIFECells Tissues Organs, 1961
- Studies Using Anterior Pituitary Hormones as Antigens.Experimental Biology and Medicine, 1959