Metabolites of Colletotrichum gloeosporioides, an Endophytic Fungus in Artemisia mongolica
- 27 September 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 63 (11) , 1529-1530
- https://doi.org/10.1021/np000204t
Abstract
A new antimicrobial metabolite, named colletotric acid (1), was isolated from a liquid culture of Colletotrichum gloeosporioides, an endophytic fungus colonized inside the stem of Artemisia mongolica. The structure was determined using spectroscopic methods (EIMS and FABMS,1H and 13C NMR, 1H−1H COSY, HMBC, and HMQC). Compound 1 inhibited the growth of Bacillus subtilis, Staphylococcus aureus, and Sarcina lutea with minimal inhibitory concentrations (MICs) of 25, 50, and 50 μg/mL, respectively, and the crop pathogenic fungus Helminthosporium sativum (MIC: 50 μg/mL).Keywords
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