Conductance fluctuations in ranvier nodes

Publisher Website
Google Scholar
Abstract
Voltage fluctuations associated with the sodium system were measured upon elimination of the potassium current in the nodal membrane by internal application of cesium-ions. The intensity of this noise reaches a maximal value at a membrane potential in the vicinity of −40 mV. Here the power spectrum consists of two additive components: a 1/f component and a Lorentzian. The Lorentzian is associated with h-gate kinetics and is consistent with the binary state conduction model. On the basis of this model the sodium-channel conductance is calculated to be2 to 5·10 −12 S. The analysis is complicated by the existence of an incomplete slow sodium inactivation process.

This publication has 9 references indexed in Scilit: