TOXICOLOGICAL APPROACHES TO METABOLITES OF FUSARIA .11. TRICHOTHECENES AND ZEARALENONE FROM FUSARIUM SPECIES ISOLATED FROM RIVER SEDIMENTS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 47  (3) , 177-184
Abstract
Fifty isolates of Fusarium spp. from river sediments were examined on their producibility of mycotoxins such as trichothecenes and zearalenone. The most frequent fungal isolate was Fusarium oxysporum, followed by F. solani and F. lateritium. When cultured on Czapek-Dox medium supplemented with peptone, more than half of these strains were suspected to produce trichothecene mycotoxins through toxicity to mice and [rabbit] reticulocyte assay method. One of the toxic isolates, F. lateritium 5036, produced the following 5 kinds of trichothecenes; diacetoxyscirpenol, 7.alpha.-hydroxydiacetoxyscirpenol, 7,8.alpha.,dihydroxy-diacetoxyscirpenol, 8.alpha.-hydroxydiacetoxyscirpenol (neosolaniol) and diacetylnivalenol. Three strains produced zearalenone on rice grain culture.

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