The conversion of the pyrrolizidine alkaloid retrorsine to pyrrolic derivatives in vivo and in vitro and its acute toxicity to various animal species
- 1 April 1973
- journal article
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 6 (4) , 207-218
- https://doi.org/10.1016/0009-2797(73)90048-3
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Acute hepatotoxicity and pyrrolic metabolites in rats dosed with pyrrolizidine alkaloidsChemico-Biological Interactions, 1972
- The conversion of pyrrolizidine alkaloids to N-oxides and to dihydropyrrolizine derivatives by rat-liver microsomes in vitroChemico-Biological Interactions, 1971
- Estimation of metabolites of pyrrolizidine alkaloids in animal tissuesAnalytical Biochemistry, 1970
- Hepatotoxic Activity of Retrorsine, Senkirkine and Hydroxysenkirkine in Newborn Rats, and the Role of Epoxides in Carcinogenesis by Pyrrolizidine Alkaloids and AflatoxinsNature, 1970
- PYRROLIZIDINE ALKALOIDS AS ALKYLATING AND ANTIMITOTIC AGENTS*Annals of the New York Academy of Sciences, 1969
- The effect of oral phenobarbitone on hepatic microsomal cytochrome P-450 and demethylation activity in rats fed normal and low protein dietsBiochemical Pharmacology, 1969
- Toxicity of Pyrrolizidine AlkaloidsNature, 1968
- The chronic pathological effects on the liver of the rat of the pyrrolizidine alkaloids heliotrine, lasiocarpine, and their N‐oxidesThe Journal of Pathology and Bacteriology, 1959
- Tables for Convenient Calculation of Median-Effective Dose (LD 50 or ED 50 ) and Instructions in Their UsePublished by JSTOR ,1952
- The action of retrorsine on rat's liverThe Journal of Pathology and Bacteriology, 1935