Total Synthesis of (−)-Mucocin
- 3 May 1999
- journal article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 38 (9) , 1263-1266
- https://doi.org/10.1002/(sici)1521-3773(19990503)38:9<1263::aid-anie1263>3.0.co;2-2
Abstract
A highly convergent, modular strategy for the total synthesis of the annonaceous acetogenin (−)‐mucocin is reported. The remarkable features are the endo‐selective formation of the tetrahydropyran ring from an activated epoxide and the stability of the butenolide in the coupling with an organomagnesium compound.Keywords
This publication has 0 references indexed in Scilit: