Inaktivierungsversuche mit homozygoten Hefestämmen verschiedenen Ploidiegrades

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Abstract
Former results of radiation inactivation in homozygous and isogenic yeast strains of different ploidy are compared with equations of target theory. For this purpose it is recessive to consider genetical and plasma lethal processes separately. The induction of recessiv lethal mutations proved to be in fair agreement with an expression developed by POLLARD and coworkers. The rising as well as the declining part of the RBE curve are explained by this equation. The calculated cross section of the target seems to be very similar to that of the cell nucleus. The plasma lethal effects are probably also in agreement with this theory. On the other hand there are difficulties in explaining the RBE curve for dominant lethal mutations in the same way.

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