Venesection in Haemoglobin Yakima, a high oxygen affinity haemoglobin
- 28 June 2008
- journal article
- case report
- Published by Wiley in Clinical and Laboratory Haematology
- Vol. 14 (3) , 195-199
- https://doi.org/10.1111/j.1365-2257.1992.tb00365.x
Abstract
High oxygen affinity haemoglobins result in polycythaemia and cardiovascular adaptation to maintain tissue oxygenation. The polycythaemia can cause symptoms of hyperviscosity and vaso-occlusive disease. We report a kindred with a high affinity haemoglobin (Haemoglobin Yakima) one of whose members gave birth to two infants with intra-uterine growth retardation and who suffered with symptoms of hyperviscosity which settled on reduction of the PCV by venesection.Keywords
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