Incorporation of fatty acids into the outer and inner membranes of isolated rat liver mitochondria
- 1 April 1969
- journal article
- Published by Wiley in FEBS Letters
- Vol. 3 (2) , 121-124
- https://doi.org/10.1016/0014-5793(69)80113-4
Abstract
Acyl‐CoA: phospholipid acyl‐transferase activity as well as phospholipase A activity were detected in inner and outer membrane preparations from rat liver mitochondria. Both enzyme systems have an optimum pH around 8 and act preferentially on phosphatidylethanolamine. While phospholipase A activity is much lower in the inner membrane than in the outer membrane of mitochondria the reverse is true for the incorporation of (14C)‐oleic acid into endogenous phosphatidylethanolamine. These results bring an indirect evidence that the inner membrane per se possesses a phospholipase A activity.Keywords
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