The incidence of allergy to propolis in 605 consecutive patients patch tested in Prague

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Abstract
605 consecutive patients were patch tested with the standard CDRG test series and with a 10% alcoholic solution of propolis. Positive allergic reactions to propolis were observed in 25 patients (4.2%); thirteen of them exhibited a simultaneous positive patch test to balsam of Peru. In view of the relatively high incidence of allergic reactions and the appearance of pseudo-cross-sensitivity to another common allergen balsam of Peru, propolis should not be used in topical medicaments or as a component of cosmetic preparations.

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