THE EFFECT OF ALTERING THYROID HORMONE CONCENTRATIONS ON PLASMA GONADOTROPHINS IN POSTMENOPAUSAL WOMEN
- 1 April 1977
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 84 (4) , 254-257
- https://doi.org/10.1111/j.1471-0528.1977.tb12572.x
Abstract
Plasma gonadotrophin levels were measured at frequent intervals in six postmenopausal thyrotoxic women treated with carbimazole. All patients showed an increasing follicle stimulating hormone/luteinizing hormone (FSH/LH) ratio as the thyroid hormone concentrations fell to normal and then into the hypothyroid range. Although the increased FSH/LH ratio was primarily due to a rise of FSH, two patients had a rise of both gonadotrophins. It is suggested that menstrual irregularities occurring in premenopausal women with disorders of thyroid metabolism may be related to similar changes.Keywords
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