THE DETERMINATION OF A REFERENCE RANGE FOR URINARY OESTROGEN EXCRETION IN LATE PREGNANCY

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Abstract
A reference range for urinary estrogen excretion between 28-40 wk has been produced by analysis of 18,870 estimations. The data were transformed logarithmically to give a Gaussian distribution on which parametric analysis was performed: non-parametric analysis was carried out on the untransformed data: the results of both analyses were compatible. Multiple pregnancies tended to have levels above the 50th centile, light-for-dates fetuses below the 50th centile. Antepartum hemorrhage showed no difference from the general reference range. Intrauterine death was preceded by a level below the 5th centile if the estimation was carried out less than 1 wk before the fetus died.

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