Age-related changes in the auditory evoked brainstem
- 1 January 1980
- journal article
- research article
- Published by Springer Nature in European Archives of Oto-Rhino-Laryngology
- Vol. 228 (4) , 249-258
- https://doi.org/10.1007/bf00660737
Abstract
Zur Erfassung altersspezifischer Veränderungen peripherer Hörbahnstationen wurden akustisch evozierte Hirnstammantworten bei Meerschweinchen zweier Altersstufen untersucht. Da Angaben über Unterschiede in der Hörleistung von Albino- und pigmentierten Meerschweinchen vorliegen, wurden beide Kollektive in die Untersuchung einbezogen. Im Latenzverhalten wiesen beide Altersstufen keine Unterschiede auf; ebenso ließ sich für die Laufzeitdifferenz der einzelnen Potentiale kein Alterseinfluß feststellen. Die Amplitude der Hirnstammantworten dagegen zeigte sich bei alten Meerschweinchen für hohe Frequenzen deutlich reduziert, wobei das dynamische Verhalten der Amplitude beider Altersgruppen keine Unterschiede aufwies. Albino- und pigmentierte Meerschweinchen entsprachen sich in beiden Altersgruppen in den Größen der untersuchten Parameter. Der Einfluß des Alterungsprozesses auf die peripheren Hörbahnstationen wird auf Grund der ermittelten Ergebnisse diskutiert. The auditory evoked brainstem responses of guinea pigs in two age groups were recorded and examined for evidence of age-dependent changes at peripheral stations in the auditory pathway. Because pigmented guinea pigs have been found to be less sensitive to sounds than albinos, both groups were included in this study. Old and young animals did not differ in response latency or in the conduction times associated with the individual potentials. By contrast, the amplitudes of the brainstem responses to high-frequency stimuli were distinctly reduced in old guinea pigs, with no difference in the dynamic of the amplitude between the two age groups. Within each age group, albino and pigmented animals resembled one another in all parameters studied. The effect of the aging process at the peripheral stations of the auditory pathway is discussed in the light of these results.This publication has 31 references indexed in Scilit:
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