Differentiation of radiation necrosis from tumor progression using proton magnetic resonance spectroscopy
- 3 March 2002
- journal article
- case report
- Published by Springer Nature in Neuroradiology
- Vol. 44 (3) , 216-222
- https://doi.org/10.1007/s002340100703
Abstract
We report on a young woman who was treated by stereotactic radiotherapy for recurrence of an initially resected low-grade astrocytoma. MRI follow-up examination 7 months after radiotherapy showed a gadolinium-DTPA-enhancing mass lesion indicative of high-grade tumor progression. This assumption was also supported by positron emission tomography with [2-18F]fluoro-2-deoxy-D–glucose (FDG-PET). In contrast, proton MR spectroscopy (1H-MRS) indicated radiation necrosis, which was confirmed histopathologically in surgical specimens. Subsequent follow-up examinations up to 19 months after surgery showed no evidence of tumor recurrence.Keywords
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