Oversized flagellar membrane protein in paralyzed mutants of Chlamydomonas reinhardrii.

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Abstract
A mutant strain of C. reinhardtii possesses an oversized flagellar membrane protein. The mutant has paralyzed flagella, is temperature sensitive for flagellar assembly, and has an abnormal axonemal protein composition. All phenotypes appear to derive from a single Mendelian mutation, and genetic analysis suggests that the mutation, called ts222, is in the gene pf1. Because pf1 mutants have radial-spoke defects a relation may exist between radial-spoke and flagellar membrane biogenesis.