BCG Vaccination
- 27 September 1951
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 245 (13) , 496-501
- https://doi.org/10.1056/nejm195109272451305
Abstract
MANY excellent articles and reviews1 , 2 on the different phases of BCG vaccination have appeared in the literature. Since a compilation of the results of these articles was thought to be of interest, the present review was prepared.In 1906 Calmette and Guérin began their experiments in an attempt to find a viable attenuated strain of bovine tubercle bacillus. In 1920, after 250 generations of growth, they finally found a strain that would produce only a localized lesion when injected into an animal. The first attempt at human vaccination with this vaccine was accomplished by Weil-Halle in 1921. Petroff and his . . .Keywords
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