Oxatomide in Seasonal Rhinoconjunctivitis

Abstract
The new antiallergic drug oxatomide [an H-1 receptor antagonist] was evaluated in 40 schoolchildren suffering from severe allergic seasonal rhinoconjunctivitis [due to deciduous tree allergy]. Antihistamine drugs had earlier given insufficient symptomatic relief. Double-blind technique was used. There was no significant different in the effect of oxatomide and the effect of the antihistamine cinnarizine in combination with phenylpropanolamine and placebo. The hypothesis that oxatomide is superior to antihistamine drugs in the treatment of severe seasonal rhinoconjunctivitis is not supported.

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