Resveratrol Derivatives and Their Role as Potassium Channels Modulators
- 20 February 2004
- journal article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 67 (3) , 421-426
- https://doi.org/10.1021/np0303153
Abstract
A series of stilbenoid analogues of resveratrol (trans-3,4',5-trihydroxystilbene) with a stilbenic or a bibenzylic skeleton have been prepared by partial synthesis from resveratrol and dihydroresveratrol. The synthesized compounds have been evaluated for their ability to modulate voltage-gated channels.Keywords
This publication has 22 references indexed in Scilit:
- KV1.1 K+ Channels Identification in Human Breast Carcinoma Cells: Involvement in Cell ProliferationBiochemical and Biophysical Research Communications, 2000
- Glucose‐ and arginine‐induced insulin secretion by human pancreatic β‐cells: the role of HERG K+channels in firing and releaseThe FASEB Journal, 2000
- Illustration of Analysis Taking into Account Complex Survey Considerations: The Association between Wine Consumption and Dementia in the PAQUID StudyAmerican Journal of Epidemiology, 1998
- Isolation, Synthesis, and Antiplatelet Aggregation Activity of Resveratrol 3-O-β-d-Glucopyranoside and Related CompoundsJournal of Natural Products, 1997
- Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro testsLife Sciences, 1997
- Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from GrapesScience, 1997
- A novel K+ channel blocker isolated from 'hiccup nut' toxinNeuroReport, 1996
- Tamoxifen: Teaching an old drug new tricks?Nature Medicine, 1996
- A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channelCell, 1995
- A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndromeCell, 1995