CYANIDE ENCEPHALOPATHY PRODUCED BY INTRAVENOUS ROUTE
- 1 September 1959
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Nervous & Mental Disease
- Vol. 129 (3) , 302-305
- https://doi.org/10.1097/00005053-195909000-00011
Abstract
Rats that received a single intravenous treatment with potassium cyanide showed brain lesions entirely similar to those produced by a single exposure to hydrogen cyanide. The production of selective white matter lesions did not depend on repetitive cyanide treatments, but rather on maintenance of optimal depth and duration of intoxication. This evidence suggests that the effect of cyanide on white matter is direct rather than indirect. Concomitant administration of 02 did not influence the results.Keywords
This publication has 3 references indexed in Scilit:
- EXPERIMENTAL CYANIDE ENCEPHALOPATHY1959
- CYANIDE LEUCOENCEPHALOPATHY IN RATS AND OBSERVATIONS ON THE VASCULAR AND FERMENT HYPOTHESES OF DEMYELINATING DISEASESJournal of Neurology, Neurosurgery & Psychiatry, 1950
- BRAIN METABOLISM INVIVO .1. THE DISTRIBUTION OF LESIONS CAUSED BY CYANIDE POISONING, INSULIN HYPOGLYCEMIA, ASPHYXIA IN NITROGEN AND FLUOROACETATE POISONING IN RATS1950