Abstract
Definition of an association between non-ejection clicks and late systolic murmurs, and the observation that patients with these physical findings usually do not manifest clinically important cardiac dysfunction are attributable to Gallavardin in the first third of the century.1 , 2 The auscultatory phenomena of non-ejection clicks and late systolic murmurs were originally thought to be due to extracardiac events and generated little interest in the cardiologic literature until abnormalities of the mitral apparatus were suggested by Barlow3 and Reid4 in the early 1960's as the source of abnormal cardiac sounds. Criley et al.,5 in 1966, then demonstrated with angiographic technic that . . .
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