An Observation of Antitoxin Titers after Booster Doses of Tetanus Toxoid

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Abstract
THE efficacy of tetanus toxoid as an agent for the prevention of clinical tetanus has been well established.1 , 2 The procedure now most widely employed is to give a basic immunizing course followed by a booster dose at least six months later. Another booster dose is then given in any emergency after an injury that might lead to tetanus infection.The protection afforded is unquestionably based in large part upon the residual titer of antitoxin persisting after primary immunization and greatly augmented by routine booster doses. Much stress has also been laid on the capacity of an emergency dose, given after . . .

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