Computer-automated prediction of the mutagenicity of benzidine, 4,4″-diaminoterphenyl, 4-dirnethylaminoazobenzene and 4-cyanodimethylaniline: comparison with the results of the Second UKEMS collaborative study
- 1 January 1986
- journal article
- research article
- Published by Oxford University Press (OUP) in Mutagenesis
- Vol. 1 (4) , 275-282
- https://doi.org/10.1093/mutage/1.4.275
Abstract
There was agreement between the experimental results, obtained in the course of the Second UKEMS Collaborative Study, for the mutagenicity in Salmonella typhimurium of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline and the mutagenicity predicted by CASE (Computer Automated Structure Evaluation), a recently developed artificial intelligence system.This publication has 5 references indexed in Scilit:
- Structure-genotoxic activity relationships of pesticides: comparison of the results from several short-term assaysMutation Research/Environmental Mutagenesis and Related Subjects, 1985
- Artificial intelligence and Bayesian decision theory in the prediction of chemical carcinogensMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1985
- Computer analysis of toxicological data bases: Mutagenicity of aromatic amines in Salmonella tester strainsEnvironmental Mutagenesis, 1985
- Artificial intelligence approach to structure-activity studies. Computer automated structure evaluation of biological activity of organic moleculesJournal of the American Chemical Society, 1984
- Structural requirements for the mutagenicity of environmental nitroarenesMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1984